008069 B6 129P2 Pvalb J
An IRES Cre pA targeting cassette containing an internal ribosome entry site IRES a Cre recombinase coding sequence a TK Neo Hygro sequence and polyadenylation site sequence was inserted into the 3 UTR of exon 5 of the parvalbumin locus Pvalb The endogenous Pvalb promoter drives expression of the Cre recombinase The construct was electroporated into 129P2 OlaHsd derived E14 embryonic